Spyre Therapeutics (SYRE) AGM 2026 summary

Opening remarks and agenda

• Meeting called to order at 12:01 P.M. Eastern Time and conducted virtually, with polls opened at the start.

• Participants instructed on voting and question submission procedures, with business items limited to those on the agenda.

• Inspector of elections, board members, management, and external advisors introduced.

• Meeting conducted per agenda and rules provided on the virtual portal.

Board and executive committee updates

• Board members and executive management team introduced, including CEO, CFO, Chief Legal Officer, and Chief Medical Officer.

• Representatives from KPMG and Ropes & Gray present.

Shareholder proposals

• Four proposals presented: election of Class I directors, advisory approval of executive compensation, ratification of KPMG as auditor, and approval of amended 2016 employee stock purchase plan.

• Board recommended voting for all proposals.