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AnaptysBio
AnaptysBio (ANAB) investor relations material
AnaptysBio TD Cowen 46th Annual Health Care Conference summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.TD Cowen 46th Annual Health Care Conference summary4 Mar, 2026
Recent accomplishments and business separation
Announced separation into two publicly traded companies: a royalty business and a biopharma operation, with Form 10 filed and completion expected in the next couple of months.
Royalty business anchored by JEMPERLI, generating significant royalties, and IMSIDOLIMAB, with a second commercial-stage royalty expected by year-end.
Biopharma business to include ANB033 (CD122 antagonist), ANB101 (BDCA-2 modulator), ROSNILIMAB, and cash, with all employees transitioning.
Stock repurchases have been executed, buying back over 11% of shares, and the royalty business will operate with minimal OpEx and high EBIT margins.
The split aims to unlock value for shareholders by creating a focused royalty entity and an unencumbered biopharma franchise.
Financial and management structure post-separation
Entered 2024 with $310 million in cash; royalty business requires minimal funding and is expected to be cash flow positive by late 2027.
Biopharma business will be allocated $100–$200 million, funding ANB033 through phase II trials and potentially additional indications.
Biopharma board will be a subset of the current board, with CEO and key executives transitioning; royalty business will have minimal management.
JEMPERLI royalty business outlook and litigation
JEMPERLI is on a $1.4 billion+ run rate, driven by strong U.S. and European launches, with further growth expected as it gains share from KEYTRUDA.
Anticipates substantial ramp-up in Europe and potential U.S. approval in rectal cancer this year, with additional pivotal trial readouts in colon and head and neck cancers.
Litigation with GSK centers on exclusivity and disclosure obligations regarding JEMPERLI combinations; trial set for July 14th in Delaware Chancery Court.
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Next AnaptysBio earnings date
Barclays 28th Annual Global Healthcare Conference10 Mar, 2026
AnaptysBio
Next AnaptysBio earnings date
Barclays 28th Annual Global Healthcare Conference10 Mar, 2026
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Frequently asked questions
AnaptysBio Inc is a clinical-stage biotechnology company. It focuses on developing immunology therapeutics aimed at autoimmune and inflammatory diseases. The company's product pipeline includes several key antibody candidates like Imsidolimab, an anti-IL-36 receptor antibody for treating generalized pustular psoriasis, currently in Phase 3 trials. Another significant product is Rosnilimab, an anti-PD-1 agonist antibody designed to address T-cell driven inflammatory diseases. Additionally, ANB032, an anti-BTLA modulator antibody, is being developed for various human inflammatory diseases linked to immune cell dysregulation. The company is headquartered in San Diego, California, and its shares are listed on the Nasdaq.
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