AstraZeneca (AZN) investor relations material

Sustainability strategy and context

• Sustainability is integrated into business strategy, focusing on climate action, health equity, and health system resilience, underpinned by science, innovation, and ethical governance.

• AI and digital tools accelerate drug discovery, improve operational efficiency, and support earlier diagnosis and targeted care.

• Business growth and decarbonization have progressed together, with an 88% reduction in Scope 1 and 2 emissions since 2015 and a target of 98% by 2026.

• Over 80% of supplier spend is with companies committed to science-based targets, and 81% of the global fleet is now electric.

• Commitment to responsible, ethical business practices and robust governance, guided by company values and executive leadership.

Climate and nature action

• Scope 3 emissions target updated to a 35% reduction by 2030 versus 2019, aligned with business growth and a net zero goal by 2045.

• $500 million invested in next-generation inhaler propellants with near zero global warming potential, already approved and in use in the UK and Europe.

• Supplier engagement includes contract requirements, renewable energy initiatives, and joint decarbonization actions.

• AZ Forest target adjusted to 100 million trees by 2030, focusing on high-quality projects and aiming for 50% waste circularity.

• Nature strategy includes eliminating horseshoe crab blood in testing and promoting sustainable sourcing.

Health equity and access

• Over 40% of genomic data now comes from underrepresented populations, supporting broader patient benefit.

• Health equity programs have positively impacted 156 million people from underserved communities since 2024.

• Aim to reach 1 billion people through medicines, clinical trials, education, and screening by 2030, with 400 million from underserved groups.

• More than 60 partnerships with NGOs through the Young Health Programme.

• Programs like Healthy Heart Africa and partnerships for newborn screening expand early detection and intervention.