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BioAge Labs (BIOA) investor relations material
BioAge Labs Q3 2025 earnings summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Q3 2025 earnings summary6 Nov, 2025
Executive summary
Advanced BGE-102, an oral CNS-penetrant NLRP3 inhibitor, into Phase 1 SAD/MAD trials for obesity and cardiovascular risk, with first participant dosed and initial data expected by year-end 2025 and full results by mid-2026.
Terminated azelaprag program in January 2025 due to safety concerns, reallocating resources to BGE-102 and APJ agonist programs, including a nanobody with >10-fold potency over apelin.
Entered collaborations with Novartis and Lilly, recognizing $5.9M in revenue YTD, with potential for up to $550M in milestones and research funding.
Completed IPO and concurrent private placement in September 2024, raising $189.5M net proceeds.
Launched new APJ agonist nanobody program in partnership with JiKang Therapeutics.
Financial highlights
Collaboration revenue was $2.1M for Q3 2025 and $5.9M for the nine months ended September 30, 2025, compared to $0 in the prior year periods.
Net loss for Q3 2025 was $20.2M ($0.56 per share), a 14% improvement year-over-year; nine-month net loss was $54.7M.
Research and development expenses decreased 8% to $18.5M in Q3 2025, mainly due to the termination of azelaprag, but increased 24% to $49.5M for the nine months, driven by BGE-102 and APJ programs.
General and administrative expenses rose 41% to $6.7M in Q3 and 60% to $20.8M for the nine months, mainly due to higher stock-based compensation, legal, personnel, and insurance costs.
Cash, cash equivalents, and marketable securities totaled $295.9M as of September 30, 2025.
Outlook and guidance
Current cash and marketable securities are expected to fund operations and capital expenses through 2029.
Initial Phase 1 SAD data for BGE-102 expected by year-end 2025; full Phase 1 results by mid-2026; proof-of-concept trial top-line data anticipated in H2 2026.
IND filings for oral and parenteral APJ agonist programs targeted for year-end 2026.
Anticipates continued net operating losses as R&D and G&A expenses increase with clinical and preclinical program advancement.
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Next BioAge Labs earnings date
Jefferies London Healthcare Conference 202517 Nov, 2025
Next BioAge Labs earnings date
Jefferies London Healthcare Conference 202517 Nov, 2025
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Frequently asked questions
BioAge Labs Inc. is a biotechnology company focused on developing therapies to extend healthy human lifespan by targeting the biological pathways of aging. The company utilizes a proprietary platform that combines machine learning, genomics, and biomarker analysis to identify and develop drug candidates aimed at treating age-related diseases, such as those affecting muscle health, immune function, and metabolism. BioAge Labs conducts research to address the underlying biological factors of aging with the goal of improving health outcomes in later life. The company is headquartered in Richmond, California, and its shares are listed on the Nasdaq.
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