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Cara Therapeutics (CARA) investor relations material

Cara Therapeutics SEO filing summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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SEO filing summary7 Oct, 2025

Company overview and business model

  • Clinical-stage biopharmaceutical company developing novel, oral small molecule therapies targeting STAT3 for fibrosis-driven diseases with significant unmet need.

  • Lead candidate TTI-101 in Phase 2 trials for idiopathic pulmonary fibrosis (IPF) and hepatocellular carcinoma (HCC); TTI-109, a related STAT3 inhibitor, in preclinical/IND stage.

  • Focus on direct STAT3 inhibition, a historically undruggable target, with differentiated mechanism and oral dosing.

  • Pipeline includes additional indications in fibrosis and oncology, with plans for further expansion.

Financial performance and metrics

  • No revenue generated to date; company has incurred significant net losses since inception.

  • Net loss of $29.4M for 2024 and $5.4M for the six months ended June 30, 2025; accumulated deficit of $97.6M as of June 30, 2025.

  • Cash and cash equivalents of $20.6M and short-term investments of $20.3M as of June 30, 2025.

  • Net income of $4.2M for Q2 2025 due to fair value changes in Convertible Notes; expects continued operating losses for the foreseeable future.

Use of proceeds and capital allocation

  • IPO is a resale registration for 2,084,117 shares by selling stockholders; company will not receive proceeds from these sales.

  • Proceeds from prior financings and merger used to fund R&D, clinical trials, and general operations.

  • Additional capital required to fund ongoing and planned clinical trials and operations; plans to seek further funding through equity, debt, or strategic partnerships.

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Q3 202513 Nov, 2025
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Frequently asked questions

Cara Therapeutics Inc is a biopharmaceutical company focused on developing and commercializing therapies for pruritus and pain management. The company’s research centers on targeting peripheral kappa opioid receptors to treat itch and pain without central nervous system side effects. Cara Therapeutics serves the healthcare sector through research-driven pharmaceutical innovations. The company is headquartered in Stamford, Connecticut, and its shares are listed on the NASDAQ.

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