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Cara Therapeutics (CARA) investor relations material
Cara Therapeutics Q3 2025 earnings summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Q3 2025 earnings summary13 Nov, 2025
Executive summary
Completed a reverse merger with Cara Therapeutics in April 2025, resulting in a new public entity and $23.9 million in net assets acquired.
Lead candidate TTI-101 in Phase 2 for HCC, with topline data expected in H1 2026; Phase 2 IPF trial did not meet goals, with high discontinuation rates due to GI adverse events and further analyses ongoing.
TTI-109, a prodrug of TTI-101, entered Phase 1 in 2025 to address tolerability issues; healthy volunteer study initiated with results anticipated in H1 2026.
No revenue generated; operations funded by equity, convertible notes, and merger proceeds.
Cash runway projected to fund operations into Q4 2026.
Financial highlights
Net loss of $5.5 million for Q3 2025 and $10.9 million for the nine months ended September 30, 2025, compared to $5.5 million and $16.7 million for the same periods in 2024.
Cash, cash equivalents, and short-term investments totaled $36.5 million as of September 30, 2025.
Accumulated deficit reached $103.2 million as of September 30, 2025.
Operating expenses increased 10.7% year-over-year for the nine-month period, driven by higher G&A costs post-merger.
$7.8 million net gain from fair value changes in convertible notes recognized in 2025.
Outlook and guidance
Topline data from ongoing REVERT Liver Cancer Phase 1b/2 trial of TTI-101 and healthy volunteer study of TTI-109 expected in H1 2026.
Substantial doubt exists about the ability to continue as a going concern; additional funding required to support operations and clinical programs.
Plans to seek further capital through equity, debt, or strategic partnerships.
Expects continued operating losses as R&D investment persists.
Current cash position expected to fund operations into Q4 2026.
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Next Cara Therapeutics earnings date
Q4 20259 Mar, 2026
Next Cara Therapeutics earnings date
Q4 20259 Mar, 2026
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Frequently asked questions
Cara Therapeutics Inc is a biopharmaceutical company focused on developing and commercializing therapies for pruritus and pain management. The company’s research centers on targeting peripheral kappa opioid receptors to treat itch and pain without central nervous system side effects. Cara Therapeutics serves the healthcare sector through research-driven pharmaceutical innovations. The company is headquartered in Stamford, Connecticut, and its shares are listed on the NASDAQ.
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