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Guardant Health (GH) investor relations material
Guardant Health Investor Day 2025 summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Investor Day 2025 summary24 Sep, 2025
Strategic vision and innovation
Mission centers on transforming cancer care through non-invasive blood-based diagnostics, expanding into multi-disease detection using the Smart Platform and Infinity AI Learning Engine.
Smart Platform and InfinityAl drive innovation, integrating genomics, epigenomics, and multimodal data for oncology, screening, and multi-disease applications.
Over 1 million patient samples have been collected, creating a unique data moat that accelerates AI-driven discovery and product development across 500+ diseases.
Shield, the blood-based CRC screening test, is expanding to multi-cancer detection, leveraging real-world data, AI, and large-scale data collection initiatives.
Strategic collaborations, such as with Quest Diagnostics and Pfizer, expand access and accelerate clinical utility studies.
Business and financial performance
2025 revenue guidance is $915–$925 million, reflecting 24–25% year-over-year growth, with oncology, biopharma, and screening all contributing.
2028 revenue target increased to $2.2 billion (34% CAGR), driven by volume growth, ASP expansion, and new product launches.
Gross margin target for 2028 is 65–70%, supported by COGS reductions, automation, and AI-driven efficiencies.
Free cash flow breakeven is now expected in Q4 2027, a year ahead of previous guidance.
Oncology and screening ASPs projected to rise, with Reveal targeting $1,000 and Guardant360 Liquid $3,300 by 2028.
Product and market leadership
Guardant360 Liquid and Tissue lead the therapy selection market, with rapid adoption of Smart Platform-powered applications and FDA PMA submission for Guardant360 Liquid.
Reveal is the leading tissue-free MRD test, with new Reveal Ultra product offering 1 ppm sensitivity and broad validation across therapies.
Shield is the first FDA-approved blood test for CRC screening, now included in NCCN guidelines and expanding to multi-cancer detection.
Biopharma business is growing at double-digit rates, with over 190 partners and expanding companion diagnostics pipeline.
Oncology business benefits from new smart applications, therapy monitoring, and international expansion.
Drivers for accelerated breakeven to Q4 2027?
Shield MCED commercial strategy and data impact
Infinity AI's competitive edge in oncology
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Next Guardant Health earnings date
Q3 202529 Oct, 2025
Next Guardant Health earnings date
Q3 202529 Oct, 2025
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Frequently asked questions
Guardant Health, Inc. is a cancer-specific diagnostic company that provides blood tests, data sets, and analytics. The company's blood test detects cancer mutations in blood so that clinicians can prescribe medicines to match specific types of cancer. The company also provides its patient data sets and analytic tools to change the way hospitals model cancer outcomes. The company is based in Redwood City, California.
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