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Guardant Health (GH) investor relations material
Guardant Health 44th Annual J.P. Morgan Healthcare Conference summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Mission and Strategic Vision
Focused on extending disease-free life and advancing human health through innovative liquid biopsy tests, diagnostics, and monitoring for earlier disease detection and improved patient outcomes, with over 1 million patients tested and $2 billion invested in R&D.
Mission to provide more time free from disease, leveraging proprietary chemistry, advanced algorithms, and Infinity AI for product innovation and future growth.
Financial Performance and Growth
Achieved $981 million in annual revenue in 2025, up 33% year-over-year, with Q4 revenue of $280 million; revenue has grown from $374 million in 2021.
Oncology test volumes grew 34% year-over-year, reaching 276,000 in 2025, driven by Guardant360, Reveal, and Tissue products.
Excluding screening, achieved positive free cash flow in Q3 and Q4 2025; ended 2025 with $1.3 billion in cash and targeting free cash flow breakeven by Q4 2027.
Product and Technology Innovation
Expanded product portfolio includes Guardant360, Reveal, and Shield, covering therapy selection, MRD, and early detection, with Shield achieving FDA approval and multi-cancer detection capabilities.
Infinity AI engine powers over 15 smart apps, leveraging >1M patient samples and >400K epigenetic profiles for clinical insights and streamlined workflows.
Launched Reveal Ultra, an ultra-sensitive MRD assay, and expanded Guardant360 and Tissue offerings with advanced applications.
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