Guardant Health (GH) investor relations material

Opening remarks and agenda

• The meeting was called to order shortly after 9:30 A.M. Pacific Time and conducted virtually to maximize accessibility for stockholders.

• The agenda and rules of conduct were made available on the meeting web portal, with procedures for voting and asking questions clearly outlined.

• The formal portion of the meeting was conducted first, followed by a Q&A session for stockholders.

Board and executive committee updates

• The Chairperson, Helmy Eltoukhy, presided over the meeting, with participation from the full Board of Directors and designated proxies.

• Representatives from Deloitte & Touche LLP (auditors) and Gunderson Dettmer (legal counsel) were present.

Shareholder proposals

• Four proposals were presented: election of Class II directors, ratification of the independent auditor, advisory approval of executive compensation, and advisory approval of the frequency of future votes on executive compensation.