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hVIVO (HVO) investor relations material

hVIVO H1 2025 earnings summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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H1 2025 earnings summary23 Sep, 2025

Executive summary

  • Revenue for H1 2025 was £24.2M, down from £35.6M in H1 2024, reflecting sector headwinds, lower HCT activity, and contract delays.

  • EBITDA (pre-exceptionals) was £3.0M, with margin dropping to 12.5% from 24.5% in H1 2024; underlying core business EBITDA was £3.5M after acquisition losses.

  • Cash position at period end was £23.3M, down from £37.1M, with no debt, impacted by acquisitions and lower advance receipts.

  • Integration of CRS and Cryostore acquisitions is nearly complete, delivering sales synergies, cost savings, and operational improvements.

  • Diversification strategy is driving growth in hLAB and Clinical Services, with strong pipelines and new contract awards.

Financial highlights

  • Revenue declined 32% year-over-year to £24.2M in H1 2025, mainly due to reduced HCT activity.

  • EBITDA margin dropped to 12.5% from 24.5% in H1 2024; adjusted basic EPS was 0.29p, down from 0.81p.

  • Cash balance declined to £23.3M, with no debt.

  • Orderbook reduced to £40M from £71M in H1 2024, with a diversified pipeline and strong interest in new service lines.

  • Operational efficiencies led to a 24-25% reduction in headcount year-over-year.

Outlook and guidance

  • FY25 revenue guidance is £47M, with low single-digit EBITDA loss expected for the full year.

  • High single-digit revenue growth anticipated in 2026 as HCT activity normalises and diversification reduces volatility.

  • 2027 expected to see a return to profitability and stronger cash generation.

  • Long-term target of £100M revenue remains, but timeline is flexible due to market volatility.

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Frequently asked questions

hVIVO plc is a contract research organization (CRO) based in the United Kingdom, specializing in the testing of vaccines and antiviral treatments using human challenge clinical trials. The company is a global leader in this niche field, focusing on infectious and respiratory diseases. hVIVO works with major pharmaceutical companies, providing early clinical development services and testing products in areas like RSV, influenza, COVID-19, and other respiratory conditions. The company is headquartered in London, UK, and its shares are listed on the LSE.

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