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Visual21 Nov 2025
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Immunocore Holdings (IMCR) investor relations material
Immunocore Holdings Jefferies London Healthcare Conference 2025 summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Jefferies London Healthcare Conference 2025 summary19 Nov, 2025
Company overview and platform differentiation
Commercial-stage biotech with operations in Oxford and the US, pioneering T-cell engager platform for oncology, infectious disease, and autoimmune indications.
Platform is modular, allowing for up- or down-modulation of the immune system, validated clinically and commercially with KIMMTRAK.
Differentiation lies in proprietary HLA–peptide library and modular effector design, enabling flexibility for future applications.
KIMMTRAK commercial performance and growth
Achieved over $100 million in quarterly sales for the first time, with strong momentum in both US and international markets.
US market penetration at 68%, with further growth targeted in community settings; Europe shows up to 90% penetration in some markets.
Duration of therapy has increased to 14 months in real-world settings, surpassing clinical trial results.
Consistent duration of therapy across regions, with long-term survival data to be published, including five-year real-world outcomes.
Pipeline and clinical development
KIMMTRAK in two Phase 3 trials: third-line cutaneous melanoma (enrollment completion expected H1 2026, data in H2 2026) and adjuvant setting (enrollment ongoing globally).
PRAME BiSpecific in Phase 3 for first-line melanoma in combination with Nivolumab; enrollment progressing well, with earliest data readout expected end of 2027 or early 2028.
Additional PRAME programs in ovarian and lung cancers, with data expected next year; half-life extended PRAME in dose escalation.
Detail US community penetration strategy for KIMMTRAK
What PRAME/Nivo combo data defines phase 3 success?
How does T1D data validate autoimmune platform?
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Next Immunocore Holdings earnings date
Q4 202526 Feb, 2026
Next Immunocore Holdings earnings date
Q4 202526 Feb, 2026
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Leroy DaleyApp Store
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Frequently asked questions
Immunocore Holdings plc is a commercial-stage biotechnology company focused on the development of innovative immunotherapies for cancer, infectious diseases, and autoimmune diseases. Utilizing its proprietary T cell receptor (TCR) technology, the company aims to create transformative medicines to address unmet medical needs. Among its notable products is KIMMTRAK, designed for the treatment of patients with unresectable or metastatic uveal melanoma. Immunocore is headquartered in Abingdon, the United Kingdom, and is listed on the NASDAQ stock exchange under the ticker symbol IMCR.
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