Kiniksa Pharmaceuticals International
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Kiniksa Pharmaceuticals International (KNSA) investor relations material

Kiniksa Pharmaceuticals International Q3 2026 earnings summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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Q3 2026 earnings summary27 Oct, 2026

Executive summary

  • Q3 2026 ARCALYST revenue was $286.0M versus $180.9M a year earlier; net income rose to $47.3M from $18.4M.

  • 2026 ARCALYST revenue guidance increased to $1.045B-$1.050B as adoption grew.

  • PASTORALE, the pivotal Phase 3 KPL-387 trial, was enrolling and dosing; data are expected in H2 2027.

Financial highlights

  • Q3 revenue was $286.0M versus $180.9M; 9M revenue was $743.8M versus $475.4M.

  • Q3 operating income was $54.2M versus $24.0M, and net income was $47.3M versus $18.4M.

  • Q3 R&D expense was $32.8M versus $24.2M; SG&A was $65.4M versus $49.1M.

  • ARCALYST collaboration operating profit increased to $211.6M from $126.6M; collaboration expense was $105.8M versus $63.3M.

  • 9M operating cash flow was $144.9M versus $84.1M.

Outlook and guidance

  • 2026 ARCALYST net revenue guidance rose to $1.045B-$1.050B from $980M-$995M.

  • 2026 R&D expense guidance was $160M-$170M and SG&A guidance was $270M-$280M; the current operating plan was expected to remain annually cash-flow positive.

  • KPL-387 Phase 3 data are expected in H2 2027, with potential commercialization targeted for 2028-2029.

  • KPL-1161's Phase 1 first-in-human trial was expected to begin by year-end 2026, targeting quarterly subcutaneous dosing.

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Frequently asked questions

Kiniksa Pharmaceuticals International, plc is a commercial-stage biopharmaceutical company focused on discovering, acquiring, developing, and commercializing therapeutic medicines. The company's work targets debilitating diseases with significant unmet medical needs, particularly within cardiovascular and autoimmune disorders. Kiniksa's portfolio includes products and candidates based on strong biological rationale or validated mechanisms, offering potential differentiation in treatment approaches. The company is known for its flagship product, ARCALYST, which is used to treat certain inflammatory cardiovascular conditions. The company is headquarted in London, UK, and its shares are listed on the NASDAQ.