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NeurAxis (NRXS) investor relations material

NeurAxis Lytham Partners Fall 2025 Investor Conference summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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Lytham Partners Fall 2025 Investor Conference summary30 Sep, 2025

Company overview and technology

  • Focuses on pediatric GI disorders, with FDA indications for functional abdominal pain and functional dyspepsia in children aged 8–21.

  • Utilizes a percutaneous electrical nerve field stimulator (IB-Stim) for neuromodulation, worn for five days per week over four weeks.

  • Mechanism targets cranial nerves via the auricular area, modulating the amygdala to alleviate symptoms.

  • Strong clinical and real-world data support efficacy, with significant results at 6 and 12 months post-treatment.

Unmet need and market opportunity

  • No FDA-approved treatments existed for decades; children relied on off-label drugs with black box warnings.

  • IB-Stim is the first FDA-cleared, evidence-backed, and safe alternative for these conditions.

  • Approximately 1 million U.S. children are severely affected, missing three or more days of school weekly.

  • Estimated $5 billion revenue opportunity at full market penetration.

Reimbursement and coverage challenges

  • Initial hurdles included lack of insurance policy coverage and no RVU credit for physicians, limiting adoption.

  • Physicians in children’s hospitals are incentivized by RVUs, but IB-Stim procedures previously offered none.

  • Hospitals and physicians faced financial disincentives, stalling broader use despite clinical support.

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Frequently asked questions

NeurAxis, Inc. is a medical technology company specializing in neuromodulation therapies aimed at addressing chronic and debilitating conditions in both children and adults. The company’s primary product, IB-Stim, utilizes Percutaneous Electrical Nerve Field Stimulation (PENFS) technology to alleviate functional abdominal pain associated with irritable bowel syndrome (IBS) in patients aged 11 to 18. The company is headquartered in Carmel, Indiana, and its shares are listed on the NYSE American.

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