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Novavax (NVAX) investor relations material
Novavax Q3 2025 earnings summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Executive summary
Achieved significant cost reductions and financial strengthening, including a drop in liabilities from $2.5B to $1.2B (2022–2024) and operating expenses from $1.7B to $728M, while transitioning to a partnership and R&D-driven model with expanded collaborations and a diversified pipeline.
Transitioned commercial responsibility for Nuvaxovid to Sanofi, achieving all 2025 milestones and securing $1.1B in non-dilutive cash over eight quarters, with expanded Sanofi partnership to pandemic flu.
Early-stage R&D pipeline advanced, targeting C. diff, shingles, RSV combination, and pandemic flu, with promising preclinical data and ongoing efforts to secure funding.
Maryland site consolidation generated $60M in near-term cash and is expected to yield $230M in long-term savings.
For the nine months ended September 30, 2025, total revenue was $976.3M, up $382.5M year-over-year, driven by APA terminations and Sanofi milestones.
Financial highlights
Q3 2025 total revenue was $70M, down 18% from $85M in Q3 2024, with product sales at $13M and licensing, royalties, and other revenue at $57M, mainly from Sanofi.
Combined R&D and SG&A expenses for Q3 2025 were $130M, an 18% reduction year-over-year; SG&A alone dropped 55%.
Non-cash charges of $126M in Q3, including $97M asset impairment and $29M loss on debt extinguishment.
Net loss for Q3 2025 was $202M, or $1.25 per diluted share, compared to $121M in Q3 2024.
Cash and equivalents plus accounts receivable totaled $812M as of September 30, 2025, with $778M in cash, cash equivalents, and marketable securities.
Outlook and guidance
Full-year 2025 adjusted total revenue guidance is $1,040M–$1,060M, with Nuvaxovid product sales of $610M (including $603M from APA terminations).
Combined R&D and SG&A expense guidance for 2025 is $505M–$535M, with non-GAAP midpoint at $450M; targets for 2026 and 2027 are $350M and $250M, respectively.
2026 adjusted total revenue expected at $185M–$205M, including a $75M milestone for manufacturing tech transfer to Sanofi.
Non-GAAP profitability now targeted as early as 2028, contingent on Sanofi CIC launch timing.
Sufficient capital is expected to fund operations for at least one year from the reporting date.
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