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PTC Therapeutics
PTC Therapeutics (PTCT) investor relations material
PTC Therapeutics 44th Annual J.P. Morgan Healthcare Conference summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.44th Annual J.P. Morgan Healthcare Conference summary12 Jan, 2026
Key business achievements and financial performance
Achieved $334 million annualized revenue run rate by Q3, with 100% year-over-year growth and GAAP profitability.
Maintained 70% gross margins despite subscale ASPs and underutilized lab capacity.
Delivered $153 million in GAAP revenue in 2024, exceeding projections, and guided 2025 revenue to $293–$299 million, with 2026 guidance raised to $415–$430 million.
Achieved profitability with only 10% of the accumulated deficits of public competitors.
Projected continued GAAP operating margin positivity for 2025 and 2026.
Technology and product innovation
Developed a patented single molecule next-generation sequencing platform enabling 10x better sensitivity and precision.
QCT technology allows for single molecule-level sensitivity, reducing noise and improving accuracy in cfDNA testing.
Unity prenatal test directly identifies fetal risk from maternal blood, detecting three times as many affected pregnancies as traditional methods.
Oncology products Northstar Select and Northstar Response offer 50%+ more actionable variant detection and earlier therapy response monitoring.
Technology enables both tumor-naive and tissue-free MRD testing, with plans to expand into early cancer detection.
Market strategy and growth drivers
Rapidly expanding test volume, with 51% year-over-year growth and increasing in-network coverage to over 250 million contracted lives.
Sales force is smaller than competitors but highly productive, adding 100 new clinics per quarter.
ASPs have surpassed $500 per test, with further growth expected from coding, contracting, and coverage improvements.
Oncology segment expected to grow faster than prenatal due to lower base and strong early indicators.
Guidance for 2026 does not depend on a specific sales rep headcount, but ongoing expansion is planned.
Sephience launch: bolus effect or sustained growth?
Votoplam accelerated approval pathway details
DMD franchise erosion: impact on 2026 guidance
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Next PTC Therapeutics earnings date
Q4 20256 Mar, 2026
PTC Therapeutics
Next PTC Therapeutics earnings date
Q4 20256 Mar, 2026
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Frequently asked questions
PTC Therapeutics Inc is a biopharmaceutical company focused on discovering, developing, and commercializing treatments for rare disorders. The company uses proprietary platforms to develop small molecules and gene therapies. Its portfolio targets genetic disorders, oncology, and neurological conditions. The company is headquartered in South Plainfield, New Jersey, and its shares are listed on the NASDAQ.
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