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Roquefort Therapeutics (ROQ) investor relations material

Roquefort Therapeutics H1 2025 earnings summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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H1 2025 earnings summary30 Sep, 2025

Executive summary

  • Announced strategic pivot from pre-clinical to clinical stage assets, highlighted by the proposed acquisition of Coiled Therapeutics, Inc., a clinical-stage oncology company with a promising Phase I asset (AO-252).

  • Signed binding agreements to sell Lyramid Pty Ltd for $10.8 million and Oncogeni Ltd for up to $12 million, with the Lyramid transaction expected to close by 31 October 2025.

  • Leadership changes included the resignation of the CEO and a Non-Executive Director, with Dr. Darrin Disley appointed as Interim Managing Director.

Financial highlights

  • Net loss for the six months ended 30 June 2025 was £467,167, an improvement from a £591,695 loss in the prior year period.

  • Cash at period end was £182,923, down from £595,662 at 30 June 2024.

  • Raised £236,000 via private placement to support working capital.

  • Basic and diluted loss per share was (0.33)p, compared to (0.45)p in the prior year period.

Outlook and guidance

  • Focused on completing the acquisition of Coiled Therapeutics and advancing AO-252 and STAT-6 programs into clinical trials.

  • Early Phase I data for AO-252 is encouraging, with plans for dose expansion in Q4 2025 and Phase III trial planning in 2026.

  • Company to be renamed Coiled Therapeutics plc and seek AIM Market admission upon transaction completion.

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H2 202528 Apr, 2026
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Frequently asked questions

Roquefort Therapeutics PLC is a United Kingdom-based biotechnology company focused on developing novel therapies targeting cancer and autoimmune diseases. The company specializes in discovering and advancing small molecule and RNA-based therapeutics through its proprietary platforms. Its operations span early-stage research, preclinical testing, and strategic collaborations for drug development. Roquefort Therapeutics PLC is headquartered in London, United Kingdom, and its shares are listed on the LSE.

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