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Sensorion (ALSEN) investor relations material
Sensorion H1 2026 earnings summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Executive summary
Focus shifted to SENS-601 gene therapy for GJB2-related hearing loss after discontinuing SENS-501 due to a changing competitive landscape and greater unmet need in GJB2 indications; SENS-601 advanced with CTAs filed in France and Canada, French approval received in August 2026, and Fast Track status granted.
SENS-401, a small molecule for hearing preservation, completed proof-of-concept and Phase II studies in three indications; partnering opportunities are being explored.
Major management changes: Fred Chereau appointed CEO in June 2026, with interim CEO Amit Munshi earlier in the year; organizational restructuring proposed post-period.
Financial highlights
Cash, cash equivalents, and short-term deposits totaled €88.5 million at June 30, 2026, up from €47.5 million at December 31, 2025.
Operating expenses rose to €24.1 million from €19.1 million, driven by higher R&D (€16.4 million, up 9% YoY) and G&A (€7.7 million) costs.
Net loss widened to €20.7 million from €16.0 million year-over-year.
Equity increased to €81.6 million from €44.5 million at year-end 2025, reflecting a €60 million capital raise.
Outlook and guidance
Cash runway expected to fund operations through end of 2027, with no liquidity risk anticipated in the next twelve months.
First patient dosing for SENS-601 targeted by early 2027; US IND and Australia CTA submissions planned by year-end 2026.
Organizational restructuring under consideration to align resources with GJB2-GT focus; may have future financial impacts.
- Gene therapy for GJB2 hearing loss enters clinic, with first dosing and data expected in 2027.ALSEN
Status update - Advancing gene therapy for GJB2 hearing loss, with clinical trials and strong financial backing.ALSEN
Corporate presentation - Advancing gene therapy and small molecule programs for hearing loss with strong clinical progress.ALSEN
Corporate presentation - Gene therapy pipeline advanced, €60m financing secured, and cash runway extended to mid-2027.ALSEN
H2 2025 - Positive clinical progress and strong cash reserves, despite a wider net loss.ALSEN
H1 2025 - Gene therapies and small molecules advance toward key milestones in hearing loss treatment.ALSEN
Corporate Presentation - Sensorion achieved major clinical milestones and secured €87.3m to fund operations into 2025.ALSEN
H1 2024 - Advancing gene therapies and small molecules, Sensorion targets global leadership in hearing loss.ALSEN
Corporate Presentation - Gene therapy pipeline advances with early clinical success and strong strategic partnerships.ALSEN
43rd Annual J.P. Morgan Healthcare Conference 2025
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