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Edge16 Oct 2026
Winner, Winner: The Chicken McNugget Story
How a 1940s breeding contest, a Cornell food scientist, and a hedge by Ray Dalio helped McDonald's turn the Chicken McNugget into a fast-food icon.
Simulations Plus
Simulations Plus (SLP) investor relations material
Simulations Plus Status update summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Status update summary16 Sep, 2026
Key product enhancements and scientific advances
ADMET Predictor 14 introduces new predictive models and descriptors to better address beyond rule of five (bRo5) molecules, such as PROTACs and macrocycles, improving predictions for solubility, permeability, and pharmacokinetics.
New models for EPSA, ChromLogD, and ChameLogK assays enable more accurate in silico predictions for properties critical to bRo5 drug candidates.
Updated ADMET risk scoring now accommodates bRo5 molecules, reducing penalties for PROTACs and macrocycles and integrating new assay predictions.
High-Throughput PK (HTPK) module enhancements include improved PK simulations for bRo5 compounds, advanced logging, and parameter sensitivity analysis for large datasets.
Command line and REST API updates provide expanded automation, new endpoints, and a command line version of ADMET Modeler for custom model building.
AI-enabled platform and workflow automation
S+ Composer, an agentic AI front-end, allows users to interact with ADMET Predictor via natural language prompts, automating complex workflows and report generation.
The platform integrates validated scientific engines, LLMs, and external databases, ensuring reliable results and extensibility for future capabilities.
Composer can autonomously process hundreds of compounds, perform multi-step analyses, generate publication-ready plots, and produce comprehensive markdown reports.
User experience and accessibility improvements
Enhanced logging and archiving features in HTPK ensure reproducibility and traceability of simulation settings and results.
New user interface options streamline loading and running saved simulation settings, and parameter sensitivity analysis is now available for multiple compounds in the GUI.
Expanded REST API endpoints and installer resources facilitate integration with existing cheminformatics infrastructures.
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Latest events from Simulations Plus
- Shareholders will vote on a merger amid litigation and enhanced disclosures on financial and governance matters.SLP
Proxy filing - Shareholders to vote on $18.50/share cash merger after robust auction and board approval.SLPProxy filing
- Shareholders to vote on $18.50/share cash merger, with board unanimous support and 26% premium.SLPProxy filing
- Q3 FY26 revenue up 7%, services up 20%, net income $3.6M, merger at $18.50/share pending.SLPQ3 2026
- Shareholders to vote on $18.50/share cash merger, with board unanimous support and 26% premium.SLPProxy filing
- Q1 revenue fell 3% to $18.4M as services rose 16%, software dropped 17%, and guidance was reaffirmed.SLPQ1 2026
- FY25 guidance targets $90M-$93M revenue, 31%-33% EBITDA margin, and expanded market reach.SLPStephens 26th Annual Investment Conference | NASH2024
- FY24 revenue up 18% to $70M; FY25 guidance strong with Pro-ficiency driving growth.SLPQ4 2024
- $100M acquisition doubles market, expands platform, and boosts 2025 EPS outlook.SLPM&A Announcement
Next Simulations Plus earnings date
Q4 202620 Nov, 2026
Simulations Plus
Next Simulations Plus earnings date
Q4 202620 Nov, 2026
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Frequently asked questions
Simulations Plus, Inc. develops drug discovery and development software for modeling and simulation, and prediction of molecular properties utilizing artificial intelligence and machine learning based technology worldwide. Through an extensive network of consultants, SPI provides insight in addition to the science of molecular modeling services and expert testimony in litigation relating to molecular property analysis, from both a scientific and business perspective. Simulations Plus, Inc. was incorporated in 1996 and is headquartered in Lancaster, California.