Terns Pharmaceuticals
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Terns Pharmaceuticals (TERN) investor relations material

Terns Pharmaceuticals has been acquired by Merck & Co Inc

Terns Pharmaceuticals Q4 2025 earnings summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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Q4 2025 earnings summary30 Mar, 2026

Executive summary

  • Entered into a definitive merger agreement with Merck Sharp & Dohme LLC on March 24, 2026, for a $53.00 per share cash tender offer, with closing expected in Q2 2026.

  • Lead asset TERN-701, an oral allosteric BCR-ABL1 inhibitor for CML, advanced through Phase 1/2 with strong efficacy and safety data; pivotal Phase 3 trials planned for late 2026 or early 2027.

  • Company remains a clinical-stage oncology firm with no commercial products and is seeking partners for legacy metabolic programs.

Financial highlights

  • Net loss for 2025 was $96.2 million, compared to $88.9 million in 2024, driven by increased R&D and G&A expenses.

  • Research and development expenses rose to $77.9 million in 2025 from $70.1 million in 2024, primarily due to higher clinical and preclinical program costs.

  • Cash, cash equivalents, and marketable securities totaled $1.02 billion as of December 31, 2025, following significant equity financings in September 2024 and December 2025.

  • No product revenue; funding primarily from equity offerings and milestone/license payments.

Outlook and guidance

  • Existing capital resources expected to fund operations into 2031.

  • Focus remains on advancing TERN-701 into pivotal trials and potential commercial launch, subject to trial outcomes and regulatory review.

  • Pending merger with Merck introduces uncertainty regarding future operations and strategic direction.

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Frequently asked questions

Terns Pharmaceuticals Inc. is a clinical-stage biopharmaceutical company focusing on the development of a diverse portfolio of small-molecule therapeutic candidates. The company's research and development efforts are primarily focused on addressing serious diseases, including oncology, non-alcoholic steatohepatitis (NASH), and obesity.