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UCB (UCB) investor relations material

UCB H1 2025 earnings summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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H1 2025 earnings summary31 Jul, 2025

Executive summary

  • Achieved 26% year-over-year net sales growth in H1 2025, with revenue reaching €3.32–€3.5B, driven by strong product launches and five key growth drivers.

  • Strategic investments in pipeline, manufacturing (notably a $2B–$5B US greenfield project), and patient access underpin future growth.

  • Upgraded full-year guidance for revenue, EBITDA margin, and core EPS based on robust H1 performance.

  • Recognized for sustainability, maintaining top sector ESG rankings.

  • Clinical pipeline advanced with positive results in multiple indications and initiation of several Phase 3 programs.

Financial highlights

  • Net sales reached €3.32B in H1 2025, up 26% year-over-year, with BIMZELX® sales quadrupling to nearly €800M.

  • Adjusted EBITDA rose 58% to €1.33B, with margin expanding to 29.6% from 23% in H1 2024.

  • Adjusted gross margin improved to 79%, driven by favorable product mix.

  • Core EPS increased 69% to €3.53 per share.

  • Operating expenses grew 15%, below net sales growth, reflecting continued investment in launches and R&D.

Outlook and guidance

  • Upgraded 2025 revenue guidance to at least €7B, EBITDA margin to at least 30%, and core EPS to at least €7.25.

  • Expect continued strong volume growth for BIMZELX® and effectiveness of US access strategy.

  • Anticipate less strong momentum in H2, with some H1 tailwinds not repeating and ongoing pricing pressure on Cimzia.

  • Currency headwinds, notably USD depreciation, expected to impact net sales by -3% for the full year, but EBITDA largely protected by hedging.

  • Continued investments planned in global launches and R&D pipeline.

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Frequently asked questions

UCB SA is a global biopharmaceutical company specializing in the discovery and development of innovative medicines and solutions for severe neurological and immunological disorders. The company's main areas of focus include treatments for conditions such as epilepsy, Parkinson's disease, and various immunological diseases. UCB operates through its biopharmaceutical segment, which develops, manufactures, and markets these therapies. The company is headquartered in Brussels, Belgium, and its shares are listed on the Euronext Brussels.

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