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Veracyte (VCYT) investor relations material

Veracyte 44th Annual J.P. Morgan Healthcare Conference summary

Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.
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44th Annual J.P. Morgan Healthcare Conference summary15 Jan, 2026

Strategic vision and platform expansion

  • Focused on transforming global cancer care through advanced molecular diagnostics, broad genomic assays, and a platform approach.

  • Platform supports risk assessment, diagnosis, prognosis, treatment guidance, and monitoring across multiple cancer types, including urology, endocrinology, pulmonology, and women's health.

  • Generates more data per test than required, creating a data-driven flywheel for growth and clinical utility.

  • Over 800,000 patients served and 600+ supporting publications as of 2025.

  • International expansion and innovation are central to long-term strategy.

Financial performance and outlook

  • 2025 revenue expected at ~$516 million, with 17% testing revenue growth, led by Afirma and Decipher.

  • Achieved >25% adjusted EBITDA margin in 2025, ahead of target, and aiming to maintain it in 2026.

  • 2026 revenue guidance of $570–$582 million, with 10–13% YOY growth and 14–16% YOY testing growth.

  • Nearly $400 million in cash and no debt, enabling both organic and inorganic growth opportunities.

  • Capital allocation prioritizes high-return projects, with a disciplined approach to M&A.

Product innovation and pipeline

  • Decipher and Afirma remain core growth drivers, with Decipher at ~33% and Afirma at ~38% market penetration by end of 2025.

  • Decipher Metastatic launched; new predictive signatures (PORTOS, PTEN) to be added in 2026.

  • Afirma transitioned to V2 transcriptome, improving scalability and result accuracy.

  • ProSigna LDT launch planned for mid-2026 in the U.S., with positive OPTIMA PRELIM study outcomes and full readout expected mid-2026.

  • True MRD platform launching in muscle-invasive bladder cancer in 1H 2026, with plans for annual new indications from 2027.

TrueMRD expansion beyond MIBC: key factors?
Capital allocation priorities with $400M cash?
Prosigna's path to share in breast prognostic market?
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Frequently asked questions

Veracyte, Inc. develops and commercializes blood tests for the early detection of lung cancer and emphysema. The company offers Veracyte Drug Screening Assay and Veracyte Acute Exacerbation Panel (V-AEP) for the detection of Lung Cancer and Chronic Obstructive Pulmonary Disease (COPD). Its drug screening assays are based on a proprietary approach of analyzing patient genomic data to predict which patients are most likely to have cancer after receiving a lung CT scan. The company markets its products through direct sales force, as well as through clinical laboratory partners, medical practitioners, and directly to patients.

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