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Xeris Biopharma Holdings (XERS) investor relations material
Xeris Biopharma Holdings Piper Sandler 37th Annual Healthcare Conference summary
Complete event summary combining all related documents: earnings call transcript, report, and slide presentation.Piper Sandler 37th Annual Healthcare Conference summary2 Dec, 2025
Business performance and financials
Achieved 42% revenue growth, raising guidance to $285M–$290M with 85% gross margins.
Became adjusted EBITDA positive in Q4 last year and reported first net income last quarter.
Reinvesting profits into business growth and pipeline development.
Recorlev commercial strategy and market dynamics
Expanded sales force by 50% in August 2024 and will double it by January, targeting 12,000 physicians.
Growth driven by increased endocrinologist awareness and screening for hypercortisolemia.
Focused on high-value prescribers, with future expansion possible as market evolves.
Payer access depends on demonstrating medical necessity; step-throughs with ketoconazole are manageable.
Competitive landscape and product positioning
New entrants like relacorilant expected to grow market awareness rather than disrupt Recorlev.
Recorlev differentiated by its mechanism of action, normalizing cortisol via synthesis inhibition.
Life cycle management includes expanding indications and label changes to build a billion-dollar brand.
Recorlev: How will new target prescribers drive growth?
XP-8121: What specific unmet needs does it address?
Keveyus: How do patient services sustain its sales?
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Next Xeris Biopharma Holdings earnings date
Q4 20259 Mar, 2026
Next Xeris Biopharma Holdings earnings date
Q4 20259 Mar, 2026
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Frequently asked questions
Xeris Biopharma Holdings Inc. is a pharmaceutical company focused on developing and commercializing innovative therapies for patients with endocrine and metabolic disorders, as well as other conditions requiring injectable treatments. The company's technology platform enables the formulation of ready-to-use injectable medications that do not require reconstitution, refrigeration, or complex preparation. The company is headquartered in Chicago, Illinois, and its shares are listed on the NASDAQ.
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