Cognition Therapeutics (CGTX) Registration Filing summary
Event summary combining transcript, slides, and related documents.
Registration Filing summary
18 Dec, 2025Company overview and business model
Clinical-stage biopharmaceutical company focused on small molecule therapeutics for age-related degenerative CNS and retinal diseases, including Alzheimer's, geographic atrophy secondary to dry AMD, and dementia with Lewy bodies.
Lead candidate zervimesine (CT1812) targets the sigma-2 receptor complex, aiming for disease modification via a novel mechanism distinct from current therapies.
Recent Phase 2 trials in Alzheimer's, DLB, and GA secondary to dry AMD showed safety, tolerability, and biomarker or clinical benefits, with ongoing and planned Phase 3 programs.
Financial performance and metrics
As of September 30, 2025, net tangible book value was $36.5 million ($0.41 per share); post-offering, adjusted net tangible book value would be $109.0 million ($0.79 per share) if the full $75 million is raised at $1.52 per share.
88,268,078 shares of common stock outstanding as of September 30, 2025; no preferred stock outstanding.
Use of proceeds and capital allocation
Net proceeds from offerings will be used for general corporate purposes, including research, clinical development, manufacturing, working capital, and capital expenditures.
Proceeds may be temporarily invested in short-term, investment-grade instruments or held as cash.
Latest events from Cognition Therapeutics
- CT-1812 slowed Alzheimer's decline by 39%; cash runway into Q2 2025, more funding needed.CGTX
Q2 20242 Feb 2026 - CT-1812 shows strong efficacy and safety in neurodegenerative trials, with key data expected soon.CGTX
H.C. Wainwright 26th Annual Global Investment Conference 202421 Jan 2026 - CT1812 slowed cognitive decline by up to 108% in low p-tau217 Alzheimer's patients.CGTX
Study Update17 Jan 2026 - Oral therapy slowed Alzheimer's decline by 39% and showed 95% protection in low-tau patients.CGTX
Life Sciences Investor Forum13 Jan 2026 - CT-1812 slowed DLB progression by up to 91% with favorable safety, supporting late-stage trials.CGTX
Study Result10 Jan 2026 - Strong Phase 2 data shifts focus to late-stage trials and extends cash runway into Q4 2025.CGTX
Q4 202426 Dec 2025 - Lead drug shows robust efficacy in neurodegeneration, with Phase III and funding plans advancing.CGTX
Life Sciences Investor Forum26 Dec 2025 - CT1812 shows strong efficacy in DLB and Alzheimer's, with rapid, well-tolerated benefits.CGTX
Piper Sandler 37th Annual Healthcare Conference7 Dec 2025 - 2025 meeting to elect directors, ratify auditor, and review governance, compensation, and ESG.CGTX
Proxy Filing2 Dec 2025